Publications

Click here to visit Dr. Gang Bao's Google Scholar Citation Page for our recent publications.

TITLE	YEAR
Detection and quantification of unintended large on-target gene modifications due to CRISPR/Cas9 editing SH Park, M Cao, G Bao Current Opinion in Biomedical Engineering, 100478	2023
High levels of lipoprotein (a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner JM Assini, JR Clark, A Youssef, C Xing, AM Doerfler, SH Park, L Saxena, … Atherosclerosis	2023
CAGE sequencing reveals CFTR-dependent dysregulation of type I IFN signaling in activated cystic fibrosis macrophages JL Gillan, M Chokshi, GR Hardisty, S Clohisey Hendry, … Science Advances 9 (21), eadg5128	2023
Force-Mediated Endocytosis of Iron Oxide Nanoparticles for Magnetic Targeting of Stem Cells L Zhang, S Hajebrahimi, S Tong, X Gao, H Cheng, Q Zhang, DT Hinojosa, … ACS Applied Materials & Interfaces	2023
In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene M De Giorgi, SH Park, A Castoreno, M Cao, A Hurley, L Saxena, … bioRxiv, 2023.07. 26.550728	2023
Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus S Vaidyanathan, R Baik, L Chen, DT Bravo, CJ Suarez, SM Abazari, … Molecular Therapy 30 (1), 223-237	2022
Comprehensive analysis and accurate quantification of unintended large gene modifications induced by CRISPR-Cas9 gene editing SH Park, M Cao, Y Pan, TH Davis, L Saxena, H Deshmukh, Y Fu, … Science Advances 8 (42), eabo7676	2022
Multiplexed high-throughput localized electroporation workflow with deep learning–based analysis for cell engineering CA Patino, N Pathak, P Mukherjee, SH Park, G Bao, HD Espinosa Science Advances 8 (29), eabn7637	2022
Multichannel power electronics and magnetic nanoparticles for selective thermal magnetogenetics B Wang, Z Li, C Sebesta, DT Hinojosa, Q Zhang, JT Robinson, G Bao, … Journal of Neural Engineering 19 (2), 026015	2022
Subsecond multichannel magnetic control of select neural circuits in freely moving flies C Sebesta, D Torres Hinojosa, B Wang, J Asfouri, Z Li, G Duret, K Jiang, … Nature Materials 21 (8), 951-958	2022
Synthesis and application of magnetic nanocrystal clusters Z Xiao, L Zhang, VL Colvin, Q Zhang, G Bao Industrial & Engineering Chemistry Research 61 (22), 7613-7625	2022
Integrating micro and nano technologies for cell engineering and analysis: toward the next generation of cell therapy workflows P Mukherjee, SH Park, N Pathak, CA Patino, G Bao, HD Espinosa ACS nano 16 (10), 15653-15680	2022
LPA disruption with AAV-CRISPR potently lowers plasma apo (a) in transgenic mouse model: A proof-of-concept study AM Doerfler, SH Park, JM Assini, A Youssef, L Saxena, AB Yaseen, … Molecular Therapy-Methods & Clinical Development 27, 337-351	2022
Multifunctional Magnetic Nanoclusters Can Induce Immunogenic Cell Death and Suppress Tumor Recurrence and Metastasis L Zhang, Q Zhang, DT Hinojosa, K Jiang, QK Pham, Z Xiao, VL Colvin, … ACS nano 16 (11), 18538-18554	2022
Characterization of Hemoglobin Variants Due to in-Frame Deletions in the β-Globin Gene from CRISPR/Cas9 Gene Correction for Sickle Cell Disease AA Pendergast, SH Park, LA Binns, CK Kanne, C Karsenty, … Blood 140 (Supplement 1), 7793-7794	2022
Fluorescent Tagging of Endogenous Beta-Globin Gene in S-HUDEP2 Cell Model for Live Cell Monitoring of Beta-Globin Expression and Regulation C Karsenty, SHJ Park, G Bao Blood 140 (Supplement 1), 12978-12979	2022
Integrated microheater array for efficient and localized heating of magnetic nanoparticles at microwave frequencies Y Fan, Q Zhang, L Zhang, G Bao, CHI Taiyun US Patent App. 17/650,982	2022
Identification and Validation of CRISPR/Cas9 Off-Target Activity in Hematopoietic Stem and Progenitor Cells SH Park, CM Lee, G Bao Stem Cell Assays: Methods and Protocols, 281-306	2022
Methods and systems for identifying nucleotide-guided nuclease off-target sites TJ Cradick, G Bao, QIU Peng US Patent 11,315,659	2022
A Sickle HUDEP2 Cell Model with GFP Tagged Beta-Globin Gene for Analyzing Unintended Phenotypic Consequences of CRISPRCas9 Gene-Editing for Treating Sickle Cell Disease CL Karsenty, SH Park, L Saxena, G Bao MOLECULAR THERAPY 30 (4), 91-92	2022
Sickle-HUDEP2 BFP Reporter Cell Model to Monitor HBG Regulation for Treating beta-Hemoglobinopathies BY Yoo, SH Park, G Bao MOLECULAR THERAPY 30 (4), 449-449	2022
The NIH somatic cell genome editing program K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, … Nature 592 (7853), 195-204	2021
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease A Lattanzi, J Camarena, P Lahiri, H Segal, W Srifa, CA Vakulskas, … Science translational medicine 13 (598), eabf2444	2021
Genome editing of donor-derived T cells to generate allogeneic chimeric antigen receptor-modified T cells: optimizing αβ T-cell-depleted haploidentical hematopoietic stem cell …V Wiebking, CM Lee, N Mostrel, P Lahiri, R Bak, G Bao, MG Roncarolo, … Haematologica 106 (3), 847	2021
Tools for experimental and computational analyses of off-target editing by programmable nucleases XR Bao, Y Pan, CM Lee, TH Davis, G Bao Nature protocols 16 (1), 10-26	2021
Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer B Saha, T Mathur, JJ Tronolone, M Chokshi, GK Lokhande, A Selahi, … Science Advances 7 (30), eabg5283	2021
CRISPR/Cas9 gene editing for curing sickle cell disease SH Park, G Bao Transfusion and Apheresis Science 60 (1), 103060	2021
The TRACE-Seq method tracks recombination alleles and identifies clonal reconstitution dynamics of gene targeted human hematopoietic stem cells R Sharma, DP Dever, CM Lee, A Azizi, Y Pan, J Camarena, T Köhnke, … Nature Communications 12 (1), 472	2021
Magnetic iron oxide nanoparticles for biomedical applications K Jiang, L Zhang, G Bao Current Opinion in Biomedical Engineering 20, 100330	2021
In vivo genome editing at the albumin locus to treat methylmalonic acidemia JL Schneller, CM Lee, LE Venturoni, RJ Chandler, A Li, S Myung, … Molecular Therapy-Methods & Clinical Development 23, 619-632	2021
Targeting the Apoa1 locus for liver-directed gene therapy M De Giorgi, A Li, A Hurley, M Barzi, AM Doerfler, NA Cherayil, HE Smith, … Molecular Therapy-Methods & Clinical Development 21, 656-669	2021
Controlled oxidation and surface modification increase heating capacity of magnetic iron oxide nanoparticles K Jiang, Q Zhang, DT Hinojosa, L Zhang, Z Xiao, Y Yin, S Tong, VL Colvin, … Applied Physics Reviews 8 (3)	2021
Sub-second multi-channel magnetic control of select neural circuits in behaving flies C Sebesta, D Torres, B Wang, J Asfouri, Z Li, G Duret, K Jiang, Z Xiao, … bioRxiv, 2021.03. 15.435264	2021
An Integrated Microheater Array With Closed-Loop Temperature Regulation Based on Ferromagnetic Resonance of Magnetic Nanoparticles Y Fan, L Zhang, Q Zhang, G Bao, T Chi IEEE Transactions on Biomedical Circuits and Systems 15 (6), 1236-1249	2021
Magnetic forces enable control of biological processes in vivo G Bao Journal of Applied Mechanics 88 (3), 030801	2021
High Bandwidth Power Electronics and Magnetic Nanoparticles for Multichannel Magnetogenetic Neurostimulation B Wang, Z Li, CE Sebesta, DT Hinojosa, Q Zhang, JT Robinson, G Bao, … bioRxiv, 2021.06. 23.447876	2021
18.3 an integrated thermal actuation/sensing array with stacked oscillators for efficient and localized heating of magnetic nanoparticles with sub-millimeter spatial resolution Y Fan, L Zhang, Q Zhang, G Bao, T Chi 2021 IEEE International Solid-State Circuits Conference (ISSCC) 64, 280-282	2021
S. Aureus Cas9 Leads to Higher Sickle Mutation Correction Compared to S. Pyogenes Cas9 in Patient Hematopoietic Stem and Progenitor Cells B Yoo, SHJP Park, Y Zhang, VA Sheehan, G Bao Blood 138, 1861	2021
CRISPR/Cas9 Editing Induces High Rates of Unintended Large Gene Modifications in HSPCs from Patients with Sickle Cell Disease SHJP Park, M Cao, Y Zhang, VA Sheehan, G Bao Blood 138, 3969	2021
615: CFTR mutation-induced macrophage dysfunction in cystic fibrosis M Chokshi, G Bao Journal of Cystic Fibrosis 20, S292-S293	2021
Method for synthesizing a nuclease with reduced off-site cleavage E Fine, TJ Cradick, Y Lin, G Bao US Patent 11,120,889	2021
The Need for Transfer Learning in CRISPR-Cas Off-Target Scoring PK Kota, Y Pan, HA Vu, M Cao, RG Baraniuk, G Bao bioRxiv, 2021.08. 28.457846	2021
Lanthanide nanop article based fluorophores XR Bao, G Bao, S Tong US Patent App. 17/261,348	2021
Accurate Quantification of CRISPR/Cas9 Induced Large Deletions, Insertions and Chromosomal Rearrangements Using SMRT Sequencing with Unique Molecular Identifiers SH Park, M Cao, G Bao MOLECULAR THERAPY 29 (4), 96-96	2021
An Integrated Thermal Actuation/Sensing Array with Stacked Oscillators for Efficient and Localized Heating of Magnetic Nanoparticles with Sub-Millimeter Spatial Resolution.Y Fan, L Zhang, Q Zhang, G Bao, T Chi ISSCC, 280-282	2021
Nanoprobes for Live-Cell Gene Detection G Bao, WJ Rhee, A Tsourkas Nano-Bio-Electronic, Photonic and MEMS Packaging, 237-251	2021
AAV-CRISPR gene editing is negated by pre-existing immunity to Cas9 A Li, MR Tanner, CM Lee, AE Hurley, M De Giorgi, KE Jarrett, TH Davis, … Molecular Therapy 28 (6), 1432-1441	2020
High-efficiency, selection-free gene repair in airway stem cells from cystic fibrosis patients rescues CFTR function in differentiated epithelia S Vaidyanathan, AA Salahudeen, ZM Sellers, DT Bravo, SS Choi, … Cell Stem Cell 26 (2), 161-171. e4	2020
CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells M Goodwin, E Lee, U Lakshmanan, S Shipp, L Froessl, F Barzaghi, … Science advances 6 (19), eaaz0571	2020
Programmable assembly of iron oxide nanoparticles using DNA origami TA Meyer, C Zhang, G Bao, Y Ke Nano letters 20 (4), 2799-2805	2020
Lipid-Encapsulated Fe3O4 Nanoparticles for Multimodal Magnetic Resonance/Fluorescence Imaging L Zhang, S Tong, Q Zhang, G Bao ACS Applied Nano Materials 3 (7), 6785-6797	2020
Metabolic engineering generates a transgene-free safety switch for cell therapy V Wiebking, JO Patterson, R Martin, MK Chanda, CM Lee, W Srifa, G Bao, … Nature Biotechnology 38 (12), 1441-1450	2020
Fine-mapping within eQTL credible intervals by expression CROP-seq Y Pan, R Tian, C Lee, G Bao, G Gibson Biology Methods and Protocols 5 (1), bpaa008	2020
Site-specific post-translational surface modification of adeno-associated virus vectors using leucine zippers NN Thadani, J Yang, B Moyo, CM Lee, MY Chen, G Bao, J Suh ACS synthetic biology 9 (3), 461-467	2020
High bone microarchitecture, strength, and resistance to bone loss in MRL/MpJ mice correlates with activation of different signaling pathways and systemic factors X Sun, X Gao, Z Deng, L Zhang, K McGilvray, BC Gadomski, S Amra, … The FASEB Journal 34 (1), 789-806	2020
Pitfalls in single clone CRISPR-Cas9 mutagenesis to fine-map regulatory intervals R Tian, Y Pan, THA Etheridge, H Deshmukh, D Gulick, G Gibson, G Bao, … Genes 11 (5), 504	2020
TRACE-Seq reveals clonal reconstitution dynamics of gene targeted human hematopoietic stem cells R Sharma, DP Dever, CM Lee, A Azizi, Y Pan, J Camarena, T Köhnke, … BioRxiv, 2020.05. 25.115329	2020
CRISPR-based gene editing enables gene repair in IPEX patient cells.M Goodwin, E Lee, U Lakshmanan, S Shipp, L Froessl, F Barzaghi, …	2020
Experimental and Computational Analyses of Off-target Editing by Programmable Nucleases XR Bao, Y Pan, CM Lee, TH Davis, G Bao	2020
UNDERSTANDING THE INFLUENCE OF CFTR ON MACROPHAGE BEHAVIOR IN CYSTIC FIBROSIS USING GENE EDITING M Chokshi, G Bao PEDIATRIC PULMONOLOGY 55, S242-S243	2020
Development of a Novel Class of Self-Assembling dsRNA Cancer Therapeutics: A Proof-of-Concept Investigation V Asthana, BS Stern, Y Tang, P Bugga, A Li, A Ferguson, A Asthana, … Molecular Therapy-Oncolytics 18, 419-431	2020
In-Silico and Experimental Detection of Personalized CRISPR Off-Targets Y Pan, C Lee, H Deshmukh, G Bao MOLECULAR THERAPY 28 (4), 456-457	2020
In Vivo Genome Editing at the Albumin Locus Corrects Two New Mouse Models of Methylmalonic Acidemia (MMA) Caused by Methylmalonyl-CoA Mutase Deficiency (Mmut)JL Schneller, CM Lee, A Li, TJ Cradick, RJ Chandler, AE Hurley, … MOLECULAR THERAPY 28 (4), 419-419	2020
A Genomic Editing-Based Therapeutic Approach for RAG2 Deficiency M Pavel-Dinu, C Gardner, TA La Guardia, CA Vakulskas, C Lee, G Bao, … MOLECULAR THERAPY 28 (4), 55-56	2020
Apoa1, a Safe Harbor Locus for Therapeutic Liver Genome Editing M De Giorgi, A Li, A Hurley, M Barzi, AM Doerfler, HE Smith, CY Lin, … MOLECULAR THERAPY 28 (4), 100-101	2020
Fine-mapping within eQTL credible intervals by expression CROP Y Pan, R Tian, CM Lee, G Bao, G Gibson	2020
Microtubule-Associated Protein Mdp3 Promotes Breast Cancer Growth and Metastasis: Erratum S Xie, X Sun, X Sun, J Ran, L Zhang, D Li, M Liu, G Bao, J Zhou Theranostics 10 (12), 5527	2020
Gene correction for SCID-X1 in long-term hematopoietic stem cells M Pavel-Dinu, V Wiebking, BT Dejene, W Srifa, S Mantri, CE Nicolas, … Nature communications 10 (1), 1634	2019
Engineered materials for in vivo delivery of genome-editing machinery S Tong, B Moyo, CM Lee, K Leong, G Bao Nature Reviews Materials 4 (11), 726-737	2019
Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease SH Park, CM Lee, DP Dever, TH Davis, J Camarena, W Srifa, Y Zhang, … Nucleic acids research 47 (15), 7955-7972	2019
Magnetic iron oxide nanoparticles for disease detection and therapy S Tong, H Zhu, G Bao Materials Today 31, 86-99	2019
Spatial control of in vivo CRISPR–Cas9 genome editing via nanomagnets H Zhu, L Zhang, S Tong, CM Lee, H Deshmukh, G Bao Nature biomedical engineering 3 (2), 126-136	2019
A self-deleting AAV-CRISPR system for in vivo genome editing A Li, CM Lee, AE Hurley, KE Jarrett, M De Giorgi, W Lu, KS Balderrama, … Molecular Therapy-Methods & Clinical Development 12, 111-122	2019
Optimization of CRISPR/Cas9 delivery to human hematopoietic stem and progenitor cells for therapeutic genomic rearrangements A Lattanzi, V Meneghini, G Pavani, F Amor, S Ramadier, T Felix, … Molecular Therapy 27 (1), 137-150	2019
Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I N Gomez-Ospina, SG Scharenberg, N Mostrel, RO Bak, S Mantri, … Nature communications 10 (1), 4045	2019
Therapeutically relevant engraftment of a CRISPR-Cas9–edited HSC-enriched population with HbF reactivation in nonhuman primates O Humbert, S Radtke, C Samuelson, RR Carrillo, AM Perez, SS Reddy, … Science translational medicine 11 (503), eaaw3768	2019
Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung YC Lee, AV Kurtova, J Xiao, F Nikolos, K Hayashi, Z Tramel, A Jain, … Nature communications 10 (1), 2131	2019
Methods and systems for identifying CRISPR/Cas off-target sites TJ Cradick, G Bao, QIU Peng US Patent 10,354,746	2019
Indirect magnetic force microscopy J Sifford, KJ Walsh, S Tong, G Bao, G Agarwal Nanoscale advances 1 (6), 2348-2355	2019
Highly efficient repair of the ΔF508 mutation in airway stem cells of cystic fibrosis patients with functional rescue of the differentiated epithelia S Vaidyanathan, AA Salahudeen, ZM Sellers, DT Bravo, SS Choi, … BioRxiv, 561183	2019
Designing iron oxide nanoparticles for image guided thermal medicine applications H Ring, S Tong, Z Gao, N Manuchehrabadi, K Jiang, S Pailloux, M Dresel, …	2019
Methods and systems for identifying crispr/cas off-target sites TJ Cradick, G Bao, QIU Peng US Patent App. 16/410,395	2019
In vivo Genome Editing to Treat Methylmalonic Acidemia (MMA) Caused by Methylmalonyl-CoA Mutase Deficiency (hMUT)JL Schneller, CM Lee, A Li, TJ Cradick, RJ Chandler, AE Hurley, … MOLECULAR THERAPY 27 (4), 369-369	2019
genome editing of graft-derived T cells for post-transplant immunotherapy in combination with TCR alpha beta (+)/CD19 (+)-depleted haploidentical HSCT V Wiebking, CM Lee, N Mostrel, RO Bak, G Bao, A Bertaina, MH Porteus BONE MARROW TRANSPLANTATION 54, 183-184	2019
Magnetic control of gene delivery in vivo H Zhu, S Tong, G Bao US Patent 10,286,073	2019
Developing an Adeno-Associated Virus-Based Protein Display Platform for Modular Delivery of Gene Editing Machinery NN Thadani, J Yang, C Lee, B Moyo, B Kundu, X Gao, G Bao, J Suh MOLECULAR THERAPY 27 (4), 88-88	2019
Stable and Therapeutically Relevant Long-Term Engraftment of CRISPR/Cas9-Edited HSCs for HbF Reactivation in NHPs O Humbert, S Radtke, R Carrillo, AM Perez, S Reddy, C Lux, S Pattabhi, … MOLECULAR THERAPY 27 (4), 450-451	2019
Towards The Clinical Translation of Gene Correction in Hematopoietic Stem Cells for Sickle Cell Disease Treatment A Lattanzi, DP Dever, J Camarena, P Lahiri, H Segal, N Talbott, W Srifa, … MOLECULAR THERAPY 27 (4), 448-448	2019
Genome Edited Human Hematopoietic Stem Cells Correct Lysosomal Storage Disorders: Proof-of-Concept and Safety Studies for Mucopolysaccharidosis Type I and Gaucher Disease N Gomez-Ospina, SG Scharenberg, N Mostrel, N Raj, L Attardi, S Khan, … MOLECULAR THERAPY 27 (4), 329-329	2019
Can’t Live without” U”: Genetic Engineering of UMPS to Create Auxotrophy in Human Cells V Wiebking, JO Patterson, R Martin, MK Chanda, CM Lee, W Srifa, G Bao, … MOLECULAR THERAPY 27 (4), 454-454	2019
Self-Deletion of AAV-CRISPR Reduces Off-Target Gene Editing In Vivo A Li, CM Lee, AE Hurley, W Lu, M De Giorgi, KE Jarrett, AM Doerfler, … MOLECULAR THERAPY 27 (4), 89-89	2019
Barcoded Clonal Tracking of CRISPR-Cas9 and rAAV6-Mediated Gene Targeting in Human Hematopoietic Stem and Progenitor Cells DP Dever, R Sharma, CM Lee, A Aziz, T Koehnke, J Camarena, Y Pan, … MOLECULAR THERAPY 27 (4), 5-5	2019
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells CA Vakulskas, DP Dever, GR Rettig, R Turk, AM Jacobi, MA Collingwood, … Nature medicine 24 (8), 1216-1224	2018
Rho-associated coiled-coil kinase (ROCK) in molecular regulation of angiogenesis J Liu, Y Wada, M Katsura, H Tozawa, N Erwin, CM Kapron, G Bao, J Liu Theranostics 8 (21), 6053	2018
Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research KE Jarrett, C Lee, M De Giorgi, A Hurley, BK Gillard, AM Doerfler, A Li, … Arteriosclerosis, thrombosis, and vascular biology 38 (9), 1997-2006	2018
In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia X Pan, L Philippen, SK Lahiri, C Lee, SH Park, TA Word, N Li, KE Jarrett, … Circulation research 123 (8), 953-963	2018
Molecular mechanisms of mechanosensing and mechanotransduction in living cells A Trubelja, G Bao Extreme Mechanics Letters 20, 91-98	2018
Examination of CRISPR/Cas9 design tools and the effect of target site accessibility on Cas9 activity CM Lee, TH Davis, G Bao Experimental physiology 103 (4), 456-460	2018
Loading Lovastatin into Camptothecin–Floxuridine Conjugate Nanocapsules for Enhancing Anti-metastatic Efficacy of Cocktail Chemotherapy on Triple-negative Breast Cancer N Zhang, X Liang, C Gao, M Chen, Y Zhou, CJ Krueger, G Bao, Z Gong, … ACS applied materials & interfaces 10 (35), 29385-29397	2018
Materials and methods for treatment of hemoglobinopathies MH Porteus, TJ Cradick, G Bao, CM Lee US Patent App. 15/550,951	2018
Engineered human umbilical cord derived erythroid progenitor cells (HUDEP2) with sickle or β-thalassemia mutation: An in-vitro system for testing pharmacological induction of …SH Park, CM Lee, Y Zhang, A Chang, VA Sheehan, G Bao Blood 132, 3478	2018
Persistence of CRISPR/Cas9-edited hematopoietic stem and progenitor cells and reactivation of fetal hemoglobin in nonhuman primates O Humbert, S Radtke, RR Carillo, AM Perez, SS Reddy, LE Schefter, … Blood 132, 806	2018
Sickle Human Umbilical Cord Derived Erythroid Progenitor Cells (S-HUDEP2): An Ideal in-Vitro System for Screening Anti-Sickling Compounds for Sickle Cell Disease A Chang, SH Park, CM Lee, A Paikari, G Bao, VA Sheehan Blood 132, 3675	2018
Basic Sciences KE Jarrett, C Lee, M De Giorgi, A Hurley, BK Gillard, AM Doerfler, A Li, … Arterioscler Thromb Vasc Biol	2018
Purification of cell mixtures using molecular beacons targeting cell specific RNA YS Yoon, G Bao, K Ban, B Wile US Patent 9,994,823	2018
Nanocrystal based biomolecule detection G Bao, S Tong US Patent App. 15/816,058	2018
Somatic Editing of Ldlr with AAV-CRISPR for Atherosclerosis Studies KE Jarrett, AM Doerfler, A Hurley, RH Hsu, M De Giorgi, A Li, HJ Pownall, … Arteriosclerosis, Thrombosis, and Vascular Biology 38 (Suppl_1), A032-A032	2018
CRISPR-Enabled Gene Correction of Methylmalonic Acidemia JL Schneller, CM Lee, A Li, RJ Chandler, TJ Cradick, WR Lagor, G Bao, … MOLECULAR THERAPY 26 (5), 115-115	2018
Cell Models of Hemoglobinopathy for Screening Therapeutic Approaches CM Lee, SH Park, Y Zhang, AK Chang, A Paikari, H Deshmukh, … MOLECULAR THERAPY 26 (5), 379-379	2018
Genome Editing of Long-Term Human Hematopoietic Stem Cells for X-Linked Severe Combined Immunodeficiency M Pavel-Dinu, V Wiebking, BT Dejene, W Srifa, S Mantri, C Nicolas, … JOURNAL OF CLINICAL IMMUNOLOGY 38 (3), 365-366	2018
Nanocrystal based biomolecule detection G Bao, S Tong US Patent 9,915,651	2018
CRISPR/Cas9-based genome editing for disease modeling and therapy: challenges and opportunities for nonviral delivery HX Wang, M Li, CM Lee, S Chakraborty, HW Kim, G Bao, KW Leong Chemical reviews 117 (15), 9874-9906	2017
CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies D Gomes-Silva, M Srinivasan, S Sharma, CM Lee, DL Wagner, TH Davis, … Blood, The Journal of the American Society of Hematology 130 (3), 285-296	2017
Size-dependent heating of magnetic iron oxide nanoparticles S Tong, CA Quinto, L Zhang, P Mohindra, G Bao ACS nano 11 (7), 6808-6816	2017
Tumour-on-a-chip: microfluidic models of tumour morphology, growth and microenvironment HF Tsai, A Trubelja, AQ Shen, G Bao Journal of the Royal Society Interface 14 (131), 20170137	2017
Efficient CRISPR/Cas9-mediated genome editing using a chimeric single-guide RNA molecule H Butt, A Eid, Z Ali, MAM Atia, MM Mokhtar, N Hassan, CM Lee, G Bao, … Frontiers in plant science 8, 1441	2017
Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions Y Qiu, S Tong, L Zhang, Y Sakurai, DR Myers, L Hong, WA Lam, G Bao Nature Communications 8 (1), 15594	2017
Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease KE Jarrett, CM Lee, YH Yeh, RH Hsu, R Gupta, M Zhang, PJ Rodriguez, … Scientific reports 7 (1), 44624	2017
Genome editing for inborn errors of metabolism: advancing towards the clinic JL Schneller, CM Lee, G Bao, CP Venditti BMC medicine 15 (1), 1-12	2017
MicroRNA detection using a double molecular beacon approach: distinguishing between miRNA and pre-miRNA AM James, MB Baker, G Bao, CD Searles Theranostics 7 (3), 634	2017
Design and validation of CRISPR/Cas9 systems for targeted gene modification in induced pluripotent stem cells CM Lee, H Zhu, TH Davis, H Deshmukh, G Bao In Vitro Mutagenesis: Methods and Protocols, 3-21	2017
Preclinical development of HBB gene correction in autologous hematopoietic stem and progenitor cells to treat severe sickle cell disease DP Dever, J Camarena, C Lee, C Vakulskas, M Behlke, G Bao, M Porteus Blood 130, 4620	2017
Viral and non-viral delivery of the CRISPR-Cas9 system in human hematopoietic stem and progenitor cells A Lattanzi, V Meneghini, G Pavani, F Amor, C Antoniani, C Lee, M Porteus, … MOLECULAR THERAPY 25 (5), 299-299	2017
CRISPR-mediated HPRT knockout induces chemo resistance and enables controlled depletion of gene-modified T cells DL Wagner, T Shum, H Tashiro, CM Lee, K Parikh, D Halder, MC Gundry, … HUMAN GENE THERAPY 28 (12), A32-A33	2017
Correction of X-Linked Severe Combined Immunodeficiency in Human Hematopoietic Stem and Progenitor Cells M Pavel-Dinu, VA Wiebking, N Gomez-Ospina, RO Bak, BT Dejene, … MOLECULAR THERAPY 25 (5), 345-346	2017
A Single CRISPR-Mediated Knockout as Novel Suicide Switch and Selection Tool for Gene-Modified T Cells DL Wagner, H Tashiro, T Shum, D Halder, MC Gundry, L Brunetti, CM Lee, … MOLECULAR THERAPY 25 (5), 63-64	2017
Genome Editing Based Reactivation of Fetal Hemoglobin Expression in HSPCs for Treating Sickle Cell Disease CM Lee, SH Park, Y Zhang, H Deshmukh, TJ Cradick, V Sheehan, G Bao MOLECULAR THERAPY 25 (5), 305-305	2017
Somatic Genome Editing with AAV Vectors Generates and Corrects a Metabolic Disease WR Lagor, KE Jarrett, CM Lee, YH Yeh, RH Hsu, R Gupta, M Zhang, … MOLECULAR THERAPY 25 (5), 14-14	2017
Gene Edited Hematopoietic Stem/Progenitor Cells for Treating Sickle Cell Disease SH Park, CM Lee, Y Zhang, V Sheehan, G Bao MOLECULAR THERAPY 25 (5), 178-178	2017
Synthesis and biomedical application of metal and metaloxide nanocrystals Q Zhang, S Tong, Y Hu, G Bao, V Colvin ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253	2017
Combinatorial plasma deposition of C-based films to test cell adhesion L Minati, V Antonini, C Pederzolli, M Dalla Serra, G Bao, G Speranza Encyclopedia of Plasma Technology, 294-306	2017
The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction N Hoshyar, S Gray, H Han, G Bao Nanomedicine 11 (6), 673-692	2016
Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome M Müller, CM Lee, G Gasiunas, TH Davis, TJ Cradick, V Siksnys, G Bao, … Molecular Therapy 24 (3), 636-644	2016
The Neisseria meningitidis CRISPR-Cas9 system enables specific genome editing in mammalian cells CM Lee, TJ Cradick, G Bao Molecular Therapy 24 (3), 645-654	2016
Nuclease target site selection for maximizing on-target activity and minimizing off-target effects in genome editing CM Lee, TJ Cradick, EJ Fine, G Bao Molecular Therapy 24 (3), 475-487	2016
A burden of rare variants associated with extremes of gene expression in human peripheral blood J Zhao, I Akinsanmi, D Arafat, TJ Cradick, CM Lee, S Banskota, … The American Journal of Human Genetics 98 (2), 299-309	2016
TALENs facilitate single-step seamless SDF correction of F508del CFTR in airway epithelial submucosal gland cell-derived CF-iPSCs S Suzuki, RG Sargent, B Illek, H Fischer, A Esmaeili-Shandiz, MJ Yezzi, … Molecular Therapy-Nucleic Acids 5	2016
Treating hemoglobinopathies using gene-correction approaches: promises and challenges RN Cottle, CM Lee, G Bao Human genetics 135, 993-1010	2016
Accurate quantification of disease markers in human serum using iron oxide nanoparticle-linked immunosorbent assay L Zhang, S Tong, J Zhou, G Bao Theranostics 6 (9), 1353	2016
Controlling Iron Oxide Nanoparticle Clustering Using Dual Solvent Exchange Coating Method TA Meyer, CA Quinto, G Bao IEEE Magnetics Letters 7, e1700904	2016
Purification of cell mixtures using molecular beacons targeting cell specific RNA YS Yoon, G Bao, K Ban, B Wile US Patent 9,493,742	2016
Strategies to determine off-target effects of engineered nucleases EJ Fine, TJ Cradick, G Bao Genome Editing: The Next Step in Gene Therapy, 187-222	2016
Combinatorial Plasma Polymerization: Carbon-Based Films L Minati, V Antonini, C Pederzolli, M Dalla Serra, G Bao, G Speranza Encyclopedia of Plasma Technology-Two Volume Set, 294-306	2016
Mechanics of Endocytosis: Physical principles of nanoparticle cellular endocytosis S Zhang, H Gao, G Bao ACS nano 9 (9), 8655-8671	2015
Multifunctional superparamagnetic iron oxide nanoparticles for combined chemotherapy and hyperthermia cancer treatment CA Quinto, P Mohindra, S Tong, G Bao Nanoscale 7 (29), 12728-12736	2015
Quantifying on-and off-target genome editing A Hendel, EJ Fine, G Bao, MH Porteus Trends in biotechnology 33 (2), 132-140	2015
Genome Editing Technologies: Defining a Path to Clinic J Corrigan-Curay, M O’reilly, DB Kohn, PM Cannon, G Bao, FD Bushman, … Molecular Therapy 23 (5), 796-806	2015
Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes EJ Fine, CM Appleton, DE White, MT Brown, H Deshmukh, ML Kemp, … Scientific reports 5 (1), 10777	2015
Efficient fdCas9 synthetic endonuclease with improved specificity for precise genome engineering M Aouida, A Eid, Z Ali, T Cradick, C Lee, H Deshmukh, A Atef, … PloS one 10 (7), e0133373	2015
Single‐Cell Detection of mRNA Expression Using Nanofountain‐Probe Electroporated Molecular Beacons JP Giraldo‐Vela, W Kang, RL McNaughton, X Zhang, BM Wile, … Small 11 (20), 2386-2391	2015
Molecular beacon-based detection and isolation of working-type cardiomyocytes derived from human pluripotent stem cells R Jha, B Wile, Q Wu, AH Morris, KO Maher, MB Wagner, G Bao, C Xu Biomaterials 50, 176-185	2015
Controlled delivery of β-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjection RN Cottle, CM Lee, D Archer, G Bao Scientific Reports 5 (1), 16031	2015
Non-genetic purification of ventricular cardiomyocytes from differentiating embryonic stem cells through molecular beacons targeting IRX-4 K Ban, B Wile, KW Cho, S Kim, MK Song, SY Kim, J Singer, A Syed, … Stem cell reports 5 (6), 1239-1249	2015
CYLD regulates noscapine activity in acute lymphoblastic leukemia via a microtubule-dependent mechanism Y Yang, J Ran, L Sun, X Sun, Y Luo, B Yan Theranostics 5 (7), 656-66	2015
Systems and Methods for Improving Nuclease Specificity and Activity E Fine, TJ Cradick, Y Lin, G Bao US Patent App. 14/399,837	2015
Detection and Assessment of MicroRNA Expression in Human Disease A Mitchell, AM James, T Alexy, G Bao, CD Searles RNA and DNA Diagnostics, 333-349	2015
GENERATION OF A BRONCHIAL EPITHELIAL CELL LINE WITH DEFINED CFTR MUTATIONS BY NUCLEASE-ENHANCED SDF-MEDIATED HOMOLOGOUS REPLACEMENT FROM NON-CF 16HBE14O-CELLS S Suzuki, R Di Geronimo, C Tasto, A Guimaraes, B Illek, H Fischer, … PEDIATRIC PULMONOLOGY 50, 260-260	2015
CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences Y Lin, TJ Cradick, MT Brown, H Deshmukh, P Ranjan, N Sarode, BM Wile, … Nucleic acids research, 42, 7473-7485	2014
Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection L Ye, J Wang, AI Beyer, F Teque, TJ Cradick, Z Qi, JC Chang, G Bao, … Proceedings of the National Academy of Sciences 111 (26), 9591-9596	2014
COSMID: a web-based tool for identifying and validating CRISPR/Cas off-target sites TJ Cradick, P Qiu, CM Lee, EJ Fine, G Bao Molecular Therapy-Nucleic Acids 3	2014
TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity C Mussolino, J Alzubi, EJ Fine, R Morbitzer, TJ Cradick, T Lahaye, G Bao, … Nucleic acids research 42 (10), 6762-6773	2014
Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation Y Qiu, AC Brown, DR Myers, Y Sakurai, RG Mannino, R Tran, B Ahn, … Proceedings of the National Academy of Sciences 111 (40), 14430-14435	2014
An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage EJ Fine, TJ Cradick, CL Zhao, Y Lin, G Bao Nucleic acids research 42 (6), e42-e42	2014
Gold nanoshelled liquid perfluorocarbon magnetic nanocapsules: a nanotheranostic platform for bimodal ultrasound/magnetic resonance imaging guided photothermal tumor ablation H Ke, J Wang, S Tong, Y Jin, S Wang, E Qu, G Bao, Z Dai Theranostics 4 (1), 12	2014
Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing A Hendel, EJ Kildebeck, EJ Fine, JT Clark, N Punjya, V Sebastiano, … Cell reports 7 (1), 293-305	2014
SAPTA: a new design tool for improving TALE nuclease activity Y Lin, EJ Fine, Z Zheng, CJ Antico, RA Voit, MH Porteus, TJ Cradick, … Nucleic acids research 42 (6), e47-e47	2014
Molecular beacon–enabled purification of living cells by targeting cell type–specific mRNAs BM Wile, K Ban, YS Yoon, G Bao Nature protocols 9 (10), 2411-2424	2014
USNCTAM perspectives on mechanics in medicine G Bao, Y Bazilevs, JH Chung, P Decuzzi, HD Espinosa, M Ferrari, H Gao, … Journal of The Royal Society Interface 11 (97), 20140301	2014
Nanomedicine: tiny particles and machines give huge gains S Tong, EJ Fine, Y Lin, TJ Cradick, G Bao Annals of biomedical engineering 42, 243-259	2014
Microtubule-associated protein mdp3 promotes breast cancer growth and metastasis Tala, S Xie, X SUn, X Sun, J Ran, L Zhang, D Li, M Liu, G Bao, J Zhou Theranostics 4, 1052-61	2014
Structural responses of cells to intracellular magnetic force induced by superparamagnetic iron oxide nanoparticles H Shen, S Tong, G Bao, B Wang Physical Chemistry Chemical Physics 16 (5), 1914-1920	2014
High-throughput cellular screening of engineered nuclease activity using the single-strand annealing assay and luciferase reporter TJ Cradick, CJ Antico, G Bao Gene Correction: Methods and Protocols, 339-352	2014
Codon swapping of zinc finger nucleases confers expression in primary cells and in vivo from a single lentiviral vector C Abarrategui-Pontes, A Creneguy, R Thinard, EJ Fine, V Thepenier, … Current Gene Therapy 14, 385-376	2014
Designing and testing the activities of TAL effector nucleases Y Lin, TJ Cradick, G Bao Gene Correction: Methods and Protocols, 203-219	2014
Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models EJ Fine, TJ Cradick, G Bao Gene Correction: Methods and Protocols, 371-383	2014
Fluorogenic Peptide Probes and Assays Y Zhang, SN Dublin, G Bao US Patent App. 14/110,002	2014
DIRECTED DIFFERENTIATION OF CF-IPS CELLS INTO GENETICALLY AND FUNCTIONALLY CORRECTED AIRWAY EPITHELIAL AND INFLAMMATORY CELLS S Suzuki, RG Sargent, A Esmaeili-Shandiz, MJ Yezzi, B Illek, H Fischer, … PEDIATRIC PULMONOLOGY 49, 221-221	2014
High-purity and high-throughput isolation of cardiomyocytes from differentiating pluripotent stem cells using molecular beacons B Wile, K Ban, YS Yoon, G Bao Nat. Protocols 9, 2411-24	2014
DNA targeting specificity of RNA-guided Cas9 nucleases PD Hsu, DA Scott, JA Weinstein, FA Ran, S Konermann, V Agarwala, Y Li, … Nature biotechnology 31 (9), 827-832	2013
CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity TJ Cradick, EJ Fine, CJ Antico, G Bao Nucleic acids research, 41, 9584-92	2013
Multifunctional nanoparticles for drug delivery and molecular imaging G Bao, S Mitragotri, S Tong Annual review of biomedical engineering 15, 253-282	2013
Gold nanoshell nanomicelles for potential magnetic resonance imaging, light‐triggered drug release, and photothermal therapy Y Ma, X Liang, S Tong, G Bao, Q Ren, Z Dai Advanced functional materials 23 (7), 815-822	2013
Indocyanine green loaded SPIO nanoparticles with phospholipid-PEG coating for dual-modal imaging and photothermal therapy Y Ma, S Tong, G Bao, C Gao, Z Dai Biomaterials 34 (31), 7706-7714	2013
Substrate stiffness regulates cellular uptake of nanoparticles C Huang, PJ Butler, S Tong, HS Muddana, G Bao, S Zhang Nano letters 13 (4), 1611-1615	2013
Magnetic targeting of human mesenchymal stem cells with internalized superparamagnetic iron oxide nanoparticles N Landázuri, S Tong, J Suo, G Joseph, D Weiss, DJ Sutcliffe, DP Giddens, … Small 9 (23), 4017-4026	2013
Purification of cardiomyocytes from differentiating pluripotent stem cells using molecular beacons targeting cardiomyocyte-specific mRNA K Ban, B Wile, S Kim, HJ Park, J Byun, KW Cho, T Saafir, MK Song, SP Yu, … Circulation, 128, 1897-909	2013
Receptor-mediated delivery of engineered nucleases for genome modification Z Chen, L Jaafar, DG Agyekum, H Xiao, MF Wade, RI Kumaran, … Nucleic Acids Research 41 (19), e182-e182	2013
Tiny Grains Give Huge Gains: Nanocrystal–Based Signal Amplification for immunosorbent assays S Tong, B Ren, Z Zheng, H Shen, G Bao ACS nano 7 (6), 5142	2013
Controllable in Situ Synthesis of Magnetite Coated Silica-Core Water-Dispersible Hybrid Nanomaterials H Qu, S Tong, K Song, H Ma, G Bao, S Pincus, W Zhou, C O’Connor Langmuir 29 (33), 10573-10578	2013
The use of molecular beacons to detect and quantify microRNA MB Baker, G Bao, CD Searles Nucleic Acid Detection: Methods and Protocols, 279-287	2013
Combinatorial plasma polymerization approach to produce thin films to testing cell proliferation V Antonini, S Torrengo, L Marocchi, L Minati, MD Serra, G Bao, … Colloids Surf B Biointerfaces 113 (C), 320-329	2013
Microvascular fluidic devices, systems and methods related thereto WA Lam, M Tsai, A Kita, DR Myers, Y Sakurai, B Ahn, Y Qiu, G Bao US Patent App. 13/710,707	2013
Engineering Nano‐Probes for Live‐Cell Imaging of Gene Expression G Bao, B Wile, A Tsourkas Nano and Cell Mechanics: Fundamentals and Frontiers, 227-253	2013
Rapid gene targeting and disease gene discovery in the rat using zinc-finger nucleases A Geurts, EJ Fine, R Schilling, J Klotz, S Kalloway, J foeckler, … Physiological Genomics	2013
Quantum dot–fluorescent protein FRET probes for sensing intracellular pH AM Dennis, WJ Rhee, D Sotto, SN Dublin, G Bao ACS nano 6 (4), 2917-2924	2012
In vitro quantification of specific microRNA using molecular beacons MB Baker, G Bao, CD Searles Nucleic acids research 40 (2), e13-e13	2012
Engineering imaging probes and molecular machines for nanomedicine S Tong, TJ Cradick, Y Ma, ZF Dai, G Bao Science China Life Sciences 55, 843-861	2012
Block copolymer-based gadolinium nanoparticles as MRI contrast agents with high T1 relaxivity S Hou, S Tong, J Zhou, G Bao Nanomedicine 7 (2), 211-218	2012
Nano and Cell Mechanics: Fundamentals and Frontiers HD Espinosa, G Bao John Wiley & Sons	2012
Microfluidic devices and systems WA Lam, D Myers, Z Peng, G Bao US Patent App. 13/523,203	2012
Challenges for engineers in biomedical and clinical sciences G Bao, JC Bischof, P Decuzzi J. Nanotechnol. ENg. Med. 3, 020202	2012
Patterning the differentiation of C2C12 skeletal myoblasts P Bajaj, B Reddy Jr, L Millet, C Wei, P Zorlutuna, G Bao, R Bashir Integrative Biology 3 (9), 897-909	2011
Self-assembly of phospholipid–PEG coating on nanoparticles through dual solvent exchange S Tong, S Hou, B Ren, Z Zheng, G Bao Nano letters 11 (9), 3720-3726	2011
MicroRNA expression profile in CAD patients and the impact of ACEI/ARB M Weber, MB Baker, RS Patel, AA Quyyumi, G Bao, CD Searles Cardiology research and practice 2011	2011
Application of factor analysis to XPS valence band of superparamagnetic iron oxide nanoparticles L Minati, V Micheli, B Rossi, C Migliaresi, L Dalbosco, G Bao, S Hou, … Applied surface science 257 (24), 10863-10868	2011
Cell and molecular biomechanics: perspectives and challenges B Ji, G Bao Acta Mechanica Solida Sinica 24 (1), 27-51	2011
Delivery of molecular beacons for live-cell imaging and analysis of RNA AK Chen, WJ Rhee, G Bao, A Tsourkas RNA Detection and Visualization: Methods and Protocols, 159-174	2011
Monitoring mRNA in living cells in a 3D in vitro model using TAT-peptide linked molecular beacons JC Alexander, A Pandit, G Bao, D Connolly, Y Rochev Lab on a Chip 11 (22), 3908-3914	2011
A Biological Delivery Platform for Zinc Finger Nucleases Using Transferrin-Mediated Endocytosis SE Meiler, WS Dynan, M Porteus, DL Spector, G Bao, Z Chen, J Pandey, … Blood 118 (21), 1071	2011
Coating Optimization of Superparamagnetic Iron Oxide Nanoparticles for High T2 Relaxivity S Tong, S Hou, Z Zheng, J Zhou, G Bao Nano letters 10 (11), 4607-4613	2010
In Vivo Evaluation of 64Cu-Labeled Magnetic Nanoparticles as a Dual-Modality PET/MR Imaging Agent C Glaus, R Rossin, MJ Welch, G Bao Bioconjugate chemistry 21 (4), 715-722	2010
Variable nanoparticle-cell adhesion strength regulates cellular uptake H Yuan, J Li, G Bao, S Zhang Physical review letters 105 (13), 138101	2010
Surface ligand effects on metal-affinity coordination to quantum dots: Implications for nanoprobe self-assembly AM Dennis, DC Sotto, BC Mei, IL Medintz, H Mattoussi, G Bao Bioconjugate chemistry 21 (7), 1160-1170	2010
HuR regulates the expression of stress-sensitive genes and mediates inflammatory response in human umbilical vein endothelial cells WJ Rhee, CW Ni, Z Zheng, K Chang, H Jo, G Bao Proceedings of the National Academy of Sciences 107 (15), 6858-6863	2010
Molecular biomechanics: the molecular basis of how forces regulate cellular function G Bao, RD Kamm, W Thomas, W Hwang, DA Fletcher, AJ Grodzinsky, … Cellular and Molecular Bioengineering 3, 91-105	2010
Slow non-specific accumulation of 2′-deoxy and 2′-O-methyl oligonucleotide probes at mitochondria in live cells WJ Rhee, G Bao Nucleic acids research 38 (9), e109-e109	2010
Measuring the transport property of ZnO tetrapod using in situ nanoprobes Y Gu, J Zhou, W Mai, Y Dai, G Bao, ZL Wang Chemical Physics Letters 484 (4-6), 96-99	2010
Use of molecular beacons to image effects of titanium surface microstructure on β1 integrin expression in live osteoblast-like cells FE Lennon, CD Hermann, R Olivares-Navarrete, WJ Rhee, Z Schwartz, … Biomaterials 31 (30), 7640-7647	2010
Nanostructured Probes for In Vivo Gene Detection G Bao, P Santangelo, N Nitin, WJ Rhee Nanotechnology: Online, 143-165	2010
Size-dependent endocytosis of nanoparticles S Zhang, J Li, G Lykotrafitis, G Bao, S Suresh Advanced materials (Deerfield Beach, Fla.) 21, 419	2009
Gigantic enhancement in response and reset time of ZnO UV nanosensor by utilizing Schottky contact and surface functionalization J Zhou, Y Gu, Y Hu, W Mai, PH Yeh, G Bao, AK Sood, DL Polla, ZL Wang Applied physics letters 94 (19)	2009
Sensing caspase 3 activity with quantum dot− fluorescent protein assemblies K Boeneman, BC Mei, AM Dennis, G Bao, JR Deschamps, H Mattoussi, … Journal of the American Chemical Society 131 (11), 3828-3829	2009
Fluorescent probes for live-cell RNA detection G Bao, WJ Rhee, A Tsourkas Annual review of biomedical engineering 11, 25-47	2009
Effects of piezoelectric potential on the transport characteristics of metal-ZnO nanowire-metal field effect transistor Z Gao, J Zhou, Y Gu, P Fei, Y Hao, G Bao, ZL Wang Journal of Applied Physics 105 (11)	2009
Resonance energy transfer between luminescent quantum dots and diverse fluorescent protein acceptors IL Medintz, T Pons, K Susumu, K Boeneman, AM Dennis, D Farrell, … The Journal of Physical Chemistry C 113 (43), 18552-18561	2009
Tat peptide is capable of importing large nanoparticles across nuclear membrane N Nitin, L LaConte, WJ Rhee, G Bao Annals of biomedical engineering 37 (10), 2018-2027	2009
Simultaneous detection of mRNA and protein stem cell markers in live cells WJ Rhee, G Bao BMC biotechnology 9, 1-10	2009
Protein mechanics G Bao Experimental mechanics 49 (1), 153-164	2009
Translation inhibition reveals interaction of 2′-deoxy and 2′- O -methyl molecular beacons with mRNA targets in living cells N Nitin, WJ Rhee, G Bao Nucleic acids research 37 (15), 4977-4986	2009
Molecular beacons can assess changes in expression and 3′-polyadenylation of human eNOS mRNA R Jones, MB Baker, M Weber, DG Harrison, G Bao, CD Searles American Journal of Physiology-Cell Physiology 296 (3), C498-C504	2009
Modeling and experiments in cell and biomolecular mechanics G Bao, A Vaziri, HD Espinosa Experimental mechanics 49, 1-2	2009
Flexible piezotronic strain sensor J Zhou, Y Gu, P Fei, W Mai, Y Gao, R Yang, G Bao, ZL Wang Nano letters 8 (9), 3035-3040	2008
Piezoelectric-potential-controlled polarity-reversible Schottky diodes and switches of ZnO wires J Zhou, P Fei, Y Gu, W Mai, Y Gao, R Yang, G Bao, ZL Wang Nano letters 8 (11), 3973-3977	2008
Multifunctional magnetic nanoparticle probes for intracellular molecular imaging and monitoring G Bao, S Nie, N Nitin, L LaConte US Patent 7,459,145	2008
Quantum dot− fluorescent protein pairs as novel fluorescence resonance energy transfer probes AM Dennis, G Bao Nano Letters 8 (5), 1439-1445	2008
Mechanical− electrical triggers and sensors using piezoelectric micowires/nanowires J Zhou, P Fei, Y Gao, Y Gu, J Liu, G Bao, ZL Wang Nano letters 8 (9), 2725-2730	2008
Target accessibility and signal specificity in live-cell detection of BMP-4 mRNA using molecular beacons WJ Rhee, PJ Santangelo, H Jo, G Bao Nucleic acids research 36 (5), e30	2008
NLS peptide conjugated molecular beacons for visualizing nuclear RNA in living cells N Nitin, G Bao Bioconjugate chemistry 19 (11), 2205-2211	2008
Dual resonance energy transfer nucleic acid probes G Bao, A Tsourkas, Y Xu US Patent 7,399,591	2008
Understanding and re-engineering nucleoprotein machines to cure human disease W Dynan, Y Takeda, D Roth, G Bao Future Medicine Ltd 3 (1), 93-105	2008
Förster resonance energy transfer (FRET) between a fluorescent protein and commercially available quantum dots: a comparison AM Dennis, G Bao Colloidal Quantum Dots for Biomedical Applications III 6866, 63-73	2008
La (OH) 3 and La2O3 nanobelts—synthesis and physical properties CG Hu, H Liu, WT Dong, YY Zhang, G Bao, CS Lao, ZL Wang Advanced Materials 19 (3), 470-474	2007
Coating thickness of magnetic iron oxide nanoparticles affects R2 relaxivity LEW LaConte, N Nitin, O Zurkiya, D Caruntu, CJ O’Connor, X Hu, G Bao Journal of Magnetic Resonance Imaging: An Official Journal of the …	2007
Enhancing UV photoconductivity of ZnO nanobelt by polyacrylonitrile functionalization JH He, YH Lin, ME McConney, VV Tsukruk, ZL Wang, G Bao Journal of Applied Physics 102 (8)	2007
ZnS/Silica nanocable field effect transistors as biological and chemical nanosensors JH He, YY Zhang, J Liu, D Moore, G Bao, ZL Wang The Journal of Physical Chemistry C 111 (33), 12152-12156	2007
Dynamics of filamentous viral RNPs prior to egress PJ Santangelo, G Bao Nucleic acids research 35 (11), 3602-3611	2007
Activatable probes and methods for in vivo gene detection G Bao, N Nitin US Patent 7,297,494	2007
Hairpin Nanoprobes for Gene Detection P Santangelo, N Nitin, L LaConte, G Bao BioMEMS and Biomedical Nanotechnology: Volume II: Micro/Nano Technologies …	2007
Nanostructured probes for RNA detection in living cells P Santangelo, N Nitin, G Bao Annals of biomedical engineering 34, 39-50	2006
Dual resonance energy transfer nucleic acid probes G Bao, A Tsourkas, Y Xu US Patent 7,081,336	2006
Live-cell characterization and analysis of a clinical isolate of bovine respiratory syncytial virus, using molecular beacons P Santangelo, N Nitin, L LaConte, A Woolums, G Bao Journal of virology 80 (2), 682-688	2006
Ferromagnetic Core-shell Fe3O4-FeP nanoparticles and FeP nanoshells CG Hu, Y Li, JP Liu, YY Zhang, G Bao, B Buchine, ZL Wang Chem. Phys. Lett. 428, 343-347	2006
Diameter-dependent voltammetric properties of carbon nanotubes C Hu, Y Zhang, G Bao, Y Zhang, M Liu, ZL Wang Chemical physics letters 418 (4), 520-525	2006
Methods of detecting gene expression in normal and cancerous cells L Yang, G Bao, C Staley, C Cohen US Patent App. 10/542,117	2006
Magnetic nanoparticle probes L LaConte, N Nitin, G Bao Materials today 8 (5), 32-38	2005
New directions in mechanics ME Kassner, S Nemat-Nasser, Z Suo, G Bao, JC Barbour, LC Brinson, … Mechanics of Materials 37 (2-3), 231-259	2005
DNA functionalized single-walled carbon nanotubes for electrochemical detection C Hu, Y Zhang, G Bao, Y Zhang, M Liu, ZL Wang The Journal of Physical Chemistry B 109 (43), 20072-20076	2005
Shedding light on the dynamics of endocytosis and viral budding G Bao, XR Bao Proceedings of the National Academy of Sciences 102 (29), 9997-9998	2005
Direct visualization of mRNA colocalization with mitochondria in living cells using molecular beacons PJ Santangelo, N Nitin, G Bao Journal of Biomedical Optics 10 (4), 044025-044025-6	2005
Dual FRET molecular beacons for mRNA detection in living cells PJ Santangelo, B Nix, A Tsourkas, G Bao Nucleic acids research 32 (6), e57-e57	2004
Functionalization and peptide-based delivery of magnetic nanoparticles as an intracellular MRI contrast agent N Nitin, LEW LaConte, O Zurkiya, X Hu, G Bao JBIC Journal of Biological Inorganic Chemistry 9, 706-712	2004
Peptide‐linked molecular beacons for efficient delivery and rapid mRNA detection in living cells N Nitin, PJ Santangelo, G Kim, S Nie, G Bao Nucleic acids research 32 (6), e58-e58	2004
The effects of BclXL and Bax over-expression on stretch-injury induced neural cell death B Pfister, G Oyler, M Betenbaugh, G Bao Mech Chem Biosyst 1 (4), 233-243	2004
Engineering nanostructured probes for sensitive intracellular gene detection G Bao, A Tsourkas, PJ Santangelo Molecular & Cellular Biomechanics 1 (1), 23	2004
Cell and molecular mechanics of biological materials G Bao, S Suresh Nature materials 2 (11), 715-725	2003
The biomechanics toolbox: experimental approaches for living cells and biomolecules KJ Van Vliet, G Bao, S Suresh Acta materialia 51 (19), 5881-5905	2003
Hybridization kinetics and thermodynamics of molecular beacons A Tsourkas, MA Behlke, SD Rose, G Bao Nucleic acids research 31 (4), 1319-1330	2003
An In Vitro Uniaxial Stretch Model for Axonal Injury BJ Pfister, TP Weihs, M Betenbaugh, G Bao Annals of biomedical engineering 31, 589-598	2003
Spectroscopic features of dual fluorescence/luminescence resonance energy-transfer molecular beacons A Tsourkas, MA Behlke, Y Xu, G Bao Analytical chemistry 75 (15), 3697-3703	2003
Shedding light on health and disease using molecular beacons A Tsourkas, G Bao Briefings in Functional Genomics 1 (4), 372-384	2003
A filtration-based protein microarray technique Y Xu, G Bao Analytical chemistry 75 (20), 5345-5351	2003
Filtration-based microarray chip G Bao, Y Xu US Patent App. 10/189,923	2003
Filtration-based microarray chip G Bao, Y Xu	2003
Structure–function relationships of shared‐stem and conventional molecular beacons A Tsourkas, MA Behlke, G Bao Nucleic acids research 30 (19), 4208-4215	2002
Mechanics of biomolecules G Bao Journal of the Mechanics and Physics of Solids 50 (11), 2237-2274	2002
Hybridization of 2′‐O‐methyl and 2′‐deoxy molecular beacons to RNA and DNA targets A Tsourkas, MA Behlke, G Bao Nucleic acids research 30 (23), 5168-5174	2002
Detecting mRNA transcripts using FRET-enhanced molecular beacons A Tsourkas, G Bao ASME-PUBLICATIONS-BED 50, 169-170	2001
Conformational Dynamics of Single Protein Molecules Under Force G Bao, A Tsourkas ASME-PUBLICATIONS-BED 50, 323-324	2001
Cell mechanics: mechanical response, cell adhesion, and molecular deformation C Zhu, G Bao, N Wang Annual review of biomedical engineering 2 (1), 189-226	2000
Investigating the secretory pathway of the baculovirus‐insect cell system using a secretory green fluorescent protein PR LeDuc, EM Whiteley, G Bao, MJ Betenbaugh Biotechnology progress 16 (5), 716-723	2000
Single-molecule biomechanics: DNA and protein deformation G Bao Mechanics in Biology 242, 25-35	2000
Neural cell death following mechanical stretch injury B Pfister, G Bao, T Weihs, M Betenbaugh Annals of Biomedical Engineering 28 (SUPPL. 1)	2000
Dynamics of individual flexible polymers in a shear flow P LeDuc, C Haber, G Bao, D Wirtz Nature 399 (6736), 564-566	1999
Experimental, numerical and analytical results for bending and buckling of rectangular orthotropic plates JC Roberts, G Bao, GJ White Composite Structures 43, 289-299	1999
Real-Time Observations of the Behavior of Cells Under Controlled Pressure and Shear Loads A Tsourkas, G Bao ASME International Mechanical Engineering Congress and Exposition 16400, 115-116	1999
Crack bridging in functionally graded coatings H Cai, G Bao Int. J. Solids Structures 35, 701-717	1998
Modeling self-propagating exothermic reactions in multilayer systems S Jayaraman, AB Mann, OM Knio, D Van Heerden, G Bao, TP Weihs Mat. Res. Soc. Symp. Proc. 481, 563-568	1998
A heat transfer analysis for quartz microresonator IR sensors G Bao, W Jiang Int. J. Solids Structures 35, 3635-3653	1998
Modeling and characterizing the propagating velocity of exothermic reactions in multilayer foils A Mann, AJ Gavens, ME Reiss, D van Heerden, G Bao, TP Weihs J. Appl. Phys. 82, 1178-1188	1997
Delamination cracking in functionally graded coating/metal substrate systems G Bao, H Cai Acta Mater. 45, 1055-1066	1997
Analytic and finite element solutions for bending and buckling of orthotropic rectangular plates G Bao, W Jiang, JC Roberts Int. J. Solids Structures 34, 1797-1822	1997
Finite element modeling of stiffened and unstiffened orthotropic plates W Jiang, G Bao, JC ROberts Computers and Structures 63, 105-117	1997
Effect of etch holes on the mechanical properties of thin films WN Sharpe, R Vaidyanathan Jr, B Yuan, G Bao, RL Edwards J. Vacuum Sci. Tech. 15, 1599-1603	1997
Isotropic invariants of traceless symmetric tensors of orders three and four GF Smith, G Bao Int. J. Engr. Sci. 35, 1457-1462	1997
Thermal softening of a particlemodified tungsten-based composite under adiabatic compression PR Leduc, G Bao International journal of solids and structures 34 (13), 1563-1581	1997
Predicting the characteristics of self-propagating exothermic reactions in multilayer foils AB Mann, AJ Gavens, M Reiss, D Van Heerden, G Bao, TP Weihs J. Appl. Phys 82, 1178-1188	1997
High strain-rate deformation in particle reinforced metal matrix composites G Bao, Z Lin Acta Metall. Mater. 44, 1011-1019	1996
A curved beam model of the proximal femur for estimating stress using DXA derived structural geometry FA Mourtada, TJ Beck, DL Hauser, CB Ruff, G Bao J. Orthopaedic Research 14, 483-492	1996
Mesoscopic modeling of gradient zones in hardmetals J Rohde, S Schmauder, G Bao Computational Materials Science 7, 63-67	1996
Delamination induced buckling in orthotropic plate structures W Jiang, G Bao ASME Aerospace DIvision 52, 31-38	1996
Thermal softening of glassy particle modified tungsten PR LeDuc, G Bao ASME 1996 International Mechanical Engineering Congress and Exposition, 497-505	1996
A boundary-layer approach for analyzing penetrator/target interactions G Bao, E Rapacki Jr, S Bilyk Proceedings of 14th Army Symposium on Solid Mechanics, 197-205	1996
Fatigue cracking in fiber reinforced metal matrix composites under mechanical and thermal loads G Bao, McMeeking ASME J. Engr. Gas Turbines, and Power 118, 416-423	1996
Inverse problems for scattering by periodic structures G Bao, A Friedman Archive for rational mechanics and analysis 132 (1), 49-72	1995
Thermomechanical fatigue cracking in fiber reinforced metal matrix composites G Bao, RM McMeeking J. Mech. Phys. Solids. 43, 1433-1460	1995
Damage in a tungsten composite due to debonding at W-W grain boundaries Z Lin, G Bao Acta Metall. Mater. 43, 1765-1774	1995
On strain-rate sensitivity of metal matrices reinforced with ceramic particles G Bao Proceedings of the IUTAM Symposium and Micromechanics of Plasticity and …	1995
Multiple cracking in functionally graded coating/substrate systems G Bao, L Wang Int. J. Solids Structures 32, 2853-2871	1995
Creep analysis of fiber composites sustaining fiber damage Y Song, G Bao, CY Hui Acta Metall. Mater. 43, 2615-2623	1995
Fatigue crack growth in fiber-reinforced metal-matrix composites G Bao, RM McMeeking Acta Metall. Mater. 42, 2415-2425	1994
Intermetallic matrix composites: progress and challenges S Kumar, G Bao Composite Sci. Technology 52, 127-150	1994
On thermomechanical fatigue of fiber reinforcedmetal matrix composites G Bao, RM McMeeking Durability of Composite Materials 51, 1-12	1994
Mode I fatigue cracking in a fiber reinforced metal matrix composite DP Walls, G Bao, F Zok Acta Metall. Mater. 41, 2061-2071	1993
Crack bridging models for fiber composites with slip-dependent interfaces G Bao, Y Song J. Mech. Phys. Solids 41, 1425-1444	1993
On the strength of ductile particle reinforced brittle matrix composites G Bao, F Zok Acta Metall. Mater. 41, 3515-3524	1993
Plastic flow of a tungsten-based composite under quasi-static compression G Bao, KT Ramesh Acta Metall. Mater. 41, 2711-2719	1993
Plastic flow and damage in a tungsten based composite G Bao, Z Lin, KT Ramesh Proceedings of 13th Army Symposium on Solid Mechanics, 101-116	1993
The deformation of a tungsten-based metal-matrix composite under compression G Bao, KT Ramesh Mechanisms and Mechanics of Composites Fracture, 113-139	1993
Remarks on crack bridging concepts G Bao, Z Suo Appl. Mech. Reviews 45, 335-366	1992
Delamination R-curve phenomena due to damage Z Zuo, G Bao, B Fan J. Mech. Phys. Solids 40, 1-16	1992
The role of material orthotropy in fracture specimens for composites G Bao, S Ho, B Fan, Z Suo Int. J. Solids Structures 29, 1105-1116	1992
Damage due to fracture of brittle reinforcements in a ductile matrix G Bao Acta Metall. Mater. 40, 2547-2555	1992
The effect of inclusions on sintering O Sudre, G Bao, B Fan, FF Lange, AG Evans J. Am. Ceram. Soc. 75, 525-531	1992
Toughening in brittle systems by ductile bridging ligaments M Bannister, H Shercliff, G Bao, F Zok, MF Ashby Acta Metall. Mater 40, 1531-1537	1992
Mixed mode delamination cracking in brittle matrix composites G Bao, AG Fan, B., Evans Mech. Mater. 13, 59-66	1992
A micromechanics model for damage in metal matrix composites G Bao Damage Mechanics and Localization 142, 1-12	1992
Particle reinforcement of ductile matrices against plastic flow and creep G Bao, JW Hutchinson, RM McMeeking Acta. Metall. Mater 39, 1871-1882	1991
Orthotropy rescaling and implications for fracture in composites Z Suo, G Bao, B Fan, TC Wang Int. J. Solids Structures 28, 235-248	1991
The effects of diffusional relaxation on the creep strength of composites J Rosler, G Bao, AG Evans Acta Metall. Mater 39, 2733-2738	1991
The flow stress of dual-phase, non-hardening solids G Bao, JW Hutchinson, RM McMeeking Mech. Mater 12, 85-94	1991
The fracture energy of interfaces: an elastic indentation technique J Davis, HC Cao, G Bao, AG Evans Acta Metall. Mater 39, 1019-1024	1991
Effects of fiber failure on fatigue cracking in a Ti/SiC composite D Walls, G Bao, F Zok Scripta Metall. Mater 25, 911-916	1991
Fatigue crack growth in a Ti/SiC composite D Walls, G Bao, F Zok Mechanical Fatigue of Advanced Materials, 343-356	1991
In Fatigue of Advanced Materials D Walls, G Bao, F Zok Materials and Component Engineering Publications Ltd., Birmingham, United …	1991
Effects of interface debonding on the toughness of ductile-particle reinforced ceramics G Bao, CY Hui Int. J. Solids Structures 26, 6316-6342	1990
Models for the strength of ductile matrix composites G Bao, F Genna, JW Hutchinson, RM McMeeking Intermetallic Matrix Composites, 3-13	1990
Constitutive relations for transversely isotropic materials GF Smith, G Bao Composite Material Response: Constitutive Relations and Damage Mechanisms, 71-90	1987
Kiwon Ban, Brian Wile, 2, 6 Kyu-Won Cho, Sangsung Kim, Ming-Ke Song, 3 Sang Yoon Kim J Singer, A Syed, SP Yu, M Wagner, G Bao
Towards standardizing nuclease off-target analysis for genome editing G Bao
108: Generation of Human Induced Pluripotent Stem Cells for Modeling Catecholamine Induced Polymorphic Ventricular Tachycardia MK Preininger, DC Nguyen, C Lee, TJ Cradick, A Dalal, X Chen, …
Molecular Beacon Technology for Tissue Engineering Applications JC Alexander, A Pandit, G Bao, Y Rochev