Sickle Cell Disease
– Engraftment studies and clonal hematopoiesis (Sheehan lab)
– Gene editing outcomes in differentiated SCD HSPCs
– In vivo gene editing for treating SCD (Sheehan lab)
Cystic Fibrosis and CF-related diabetes (CFRD)
– Gene editing of CF-iPSCs and HBE cell lines
– The role of macrophages (Gary lab)
– Base editing for treating CF (Gao lab)
– Isolation of CF-iPSC derived beta cells, in vivo beta cell targeting
Cancer
– T-cell engineering (Yee lab)
– cgRNAs
Wiskott-Aldrich Syndrome (Davis Lab)
Liver disease
– Liver gene editing and donor integration into Apoai locus
Progeria Diseases (Cooke Lab)
eCROP-seq
-Fine-mapping of SNPs in autoimmune and infectious diseases (Gibson lab)